| PA-08 | Paige Cognetti (D) vs Rob Bresnahan Jr (R, inc.) | Incumbent Rob Bresnahan Jr (R) | Toss Up | Lean D | costs/healthcare/ACA/Medicaid; data centers/AI; corruption/stock trading |
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| MI-07 | William Lawrence (D) vs Tom Barrett (R, inc.) | Incumbent Tom Barrett (R) | Toss Up | Toss-up | Mason data center/local control/grid costs; prices/tariffs; healthcare |
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| MI-10 | Christina Hines (D) vs Michael Bouchard (R) | Open seat | Toss Up | Toss-up | healthcare/money in politics; tariffs/manufacturing; border/crime |
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| MT-01 | Sam Forstag (D) vs Aaron Flint (R) | Open seat | Toss Up | Toss-up | housing/healthcare/fuel; public lands/timber; data centers |
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| NY-17 | Cait Conley (D) vs Mike Lawler (R, inc.) | Incumbent Mike Lawler (R) | Toss Up | Toss-up | economy/housing; immigration/sanctuary policy; Israel/antisemitism/Iran |
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| VA-01 | Shannon Taylor (D) vs Rob Wittman (R, inc.) | Incumbent Rob Wittman (R) | Toss Up | Toss-up | affordability/groceries/housing; data centers/electricity; healthcare/ACA/rural hospitals |
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| MI-04 | Sean McCann (D) vs Bill Huizenga (R, inc.) | Incumbent Bill Huizenga (R) | Toss Up | Toss-up | energy affordability/data centers; gas/cost of living |
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| IA-02 | Lindsay James (D) vs Joe Mitchell (R) | Open seat | Toss Up | Lean D | cost of living/gas/housing/childcare/healthcare; taxes/regulation/tariffs |
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| KY-06 | Zach Dembo (D) vs Ralph Alvarado (R) | Open seat | Toss Up | Toss-up | affordability/tariffs/housing; Medicaid/rural hospitals; data centers/utility costs |
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| CA-22 | Randy Villegas (D) vs David Valadao (R, inc.) | Incumbent David Valadao (R) | Toss Up | Lean D | Medicaid/health care; water/agriculture; affordability/gas |
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| TX-15 | Bobby Pulido (D) vs Monica De La Cruz (R, inc.) | Incumbent Monica De La Cruz (R) | Toss Up | Lean D | costs/healthcare/economic opportunity; immigration/labor; water/1944 treaty |
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| NC-01 | Don Davis (D, inc.) vs Laurie Buckhout (R) | Incumbent Don Davis (D) | Toss Up | Lean D | costs/jobs/rural healthcare; NC12/flood insurance/coastal erosion; disaster recovery/fishing |
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| OH-09 | Marcy Kaptur (D, inc.) vs Derek Merrin (R) | Incumbent Marcy Kaptur (D) | Toss Up | Toss-up | costs/taxes/tariffs/energy; data centers |
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| OH-07 | Brian Poindexter (D) vs Max Miller (R, inc.) | Incumbent Max Miller (R) | Toss Up | Toss-up | costs/fuel/tariffs/healthcare; workers' bargaining rights; ethics allegations/investigation |
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| FL-14 | Kathy Castor (D, inc.) vs Mike Beltran (R) | Incumbent Kathy Castor (D) | Toss Up | Toss-up | property/flood insurance; housing/utility/health costs; abortion/immigration |
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| FL-22 | Pia Dandiya (D) vs Casey Askar (R) | Open seat | Toss Up | Toss-up | affordability/housing; ACA/health care; education/tariffs/data centers |
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| TX-35 | Johnny Garcia (D) vs Carlos De La Cruz (R) | Open seat | Toss Up | Toss-up | grocery/healthcare premiums; immigration/tariffs/employers; San Antonio military installations |
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| MN | Peggy Flanagan (D) vs Michele Tafoya (R) | Open; Tina Smith retiring. | Lean D | Lean D | program-fraud oversight; taxes; immigration |
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| NH | Chris Pappas (D) vs John E. Sununu (R) | Open; Jeanne Shaheen retiring. | Lean D | Likely D | cost of living; tariffs; Iran war |
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| AK | Mary Peltola (D) vs Dan Sullivan (R, inc.) | Incumbent Dan Sullivan (R) | Toss Up | Lean D | affordability/energy; fuel costs; fisheries/bycatch |
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| OH-special | Sherrod Brown (D) vs Jon Husted (R, inc.) | Class III special; appointed incumbent Jon Husted; remainder of the Vance term through January 2029. | Toss Up | Toss Up | affordability/prescriptions/utility costs; data-center incentives; immigration |
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| MI | Abdul El-Sayed (D) vs Mike Rogers (R) | Open; Gary Peters retiring. | Toss Up | Lean D | affordability; healthcare; Iran war |
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| ME | Troy Jackson (D) vs Susan Collins (R, inc.) | Incumbent Susan Collins (R) | Toss Up | Toss Up | cost of living/Medicaid; heating energy |
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| IA | Josh Turek (D) vs Ashley Hinson (R) | Open; Joni Ernst retiring. | Toss Up | Toss Up | tariffs; energy; healthcare costs |
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| TX | James Talarico (D) vs Ken Paxton (R) | Open November ballot, R-held after Cornyn lost the runoff. | Toss Up | Toss Up | gas/grocery/housing; utility/data centers; healthcare |
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| KS | Adam Hamilton (D) vs Roger Marshall (R, inc.) | Incumbent Roger Marshall (R) | Toss Up | Toss Up | tariffs; Iran/fuel prices; ACA/healthcare |
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| SC | Annie Andrews (D) vs Darline Graham (R, inc.) | Regular Class II race; appointed incumbent Darline Graham; not an open seat. | Lean R | Lean R | Social Security; data centers; healthcare |
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